Are you living with heart failure?

The CardiAMP Cell Therapy Trial is studying a new, investigational cell therapy for people with heart failure.

What is Ischemic Heart Failure?
The body depends on the heart’s pumping action to deliver oxygen and nutrient-rich blood to the body’s cells. When the heart muscle cannot pump enough blood to meet the body’s needs, this is called heart failure. This can cause troubling symptoms such as fatigue, shortness of breath, swelling in the legs and ankles and result in decreased physical activity.

When heart failure develops following evidence of a blocked blood vessel in the heart such as a heart attack, it is called ischemic heart failure, a serious and progressive condition that negatively impacts quality of life and survival.

Heart failure is quite common, affecting over 6 million Americans.


Current Treatment Options for Patients
Currently, there is no cure for heart failure. It is often managed using medications, healthy lifestyle changes, and medical device implants that help the heart pump more efficiently. Over time, heart failure leads to more complex therapies including an LVAD (Left Ventricular Assist Device) and heart transplantation.

More recently, cell therapy has emerged as a potential treatment option for ischemic heart failure.


Autologous Bone Marrow Mononuclear Cell Therapy
Bone marrow is a unique substance found in the center of some of the larger bones in our bodies, such as the hipbones. Bone marrow is where new blood cells are produced. For years, doctors and researchers have been studying how bone marrow cells can help stimulate the body’s natural healing response.

Autologous bone marrow mononuclear cell therapy is the use of a patient’s own bone marrow cells as a treatment.

What is CardiAMP Therapy?

CardiAMP Cell Therapy is designed for people who are living with ischemic heart failure. It is an investigational therapy that uses your own bone marrow cells to potentially stimulate the body’s natural healing response.

When these cells are injected into the heart muscle, it is believed that they release proteins that signal other cells to repair themselves, resulting in improved heart function.

Learn more about the CardiAMP Cell Therapy Trial for Heart Failure

A Patient’s Perspective: Listen to Tim’s and Michele’s Stories

Hear from our Study Physicians

Carl Pepine, MD
University of Florida

Amish Raval, MD
University of Wisconsin

Leslie Miller, MD
BayCare, Morton Plant Hospital

R. David Anderson, MD
University of Florida

Frequent Questions
Clinical studies (also called clinical trials) are used to learn about the safety and effectiveness of possible new medications, medical devices, and medical procedures. Although there are many types of clinical trials, all FDA monitored trials must conform to s strict rules set by the U.S. Food and Drug Administration (FDA). These rules help protect the rights and safety of those who volunteer to take part in clinical trials.
No, CardiAMP Cell Therapy is currently only available in the US through the CardiAMP Cell Therapy clinical trial.
If you are randomized to the control group and complete the clinical check-ups during the study, you will be given the option to receive the cell therapy after your 24-month follow-up visit.
About 260 people are expected to participate in the study.
If you join the study, your participation will last approximately 2 years. Following your procedure, you will return to your study doctor’s office for 5 follow-up visits over the first year, and then one more annual visit. These visits are an important part of the study, as they allow your doctor to closely monitor your individual results and experiences.


If you are randomly assigned to the control group of the study and choose to crossover and receive the cell therapy after your 24-month follow-up visit, then you will need to be followed for an additional year after receiving the cell therapy.
As with all clinical studies, your participation is completely voluntary, and you may choose to leave the study at any time.
As with all clinical studies, your participation is completely voluntary and you may choose to leave the study at any time.
To see if you might qualify for the CardiAMP Cell Therapy Trial for heart failure, and to be referred to a study center in your area, the next step is taking the pre-screening questionnaire. Please click here to get started.


For additional information about the CardiAMP Cell Therapy Trial for heart failure, visit:


To learn more about the Study Sponsor, BioCardia, Inc., please visit

See If You Qualify

Take a brief, anonymous survey to see if you might be eligible for the CardiAMP Cell Therapy study for Ischemic Heart Failure: